Notes...the basic idea is from valadaar and he came up with the first twelve ideas, I expanded them into a 30. Here is the link. http://strolen.com/viewing/4484#73440
This table is intended to be used when unprepared mortals tamper with things of truely dark and horrid origins. Most effects are fatal, and it is assumed that powerful magic would be required to reverse these.
1.Horrid Rotting.- At first, the flesh - starting with the area that made contact - will be subject to discoloration, psorasis, and eventually full blow rotting. Rotting moves inwards after affecting the limbs, eventually killing the victim. Severing affected parts does not help - the contamination is supernature, and rules of biology do not apply.
2. Petrification - Starts out as minor stiffening and inflammation, with arthritic effects on joints. As time goes by, nodes of stone begin forming in the being’s flesh, starting at the hands and moving to to core. These are very painful and grow in size, eventually petrifying the limb and moving inwards. Eventually, vital organs will be effected and begin failing. Cancer-like symptoms will take, causing death unless checked by powerful magic.
3. Combustion - Users flesh bursts into flame, causing damage until extinguished. Willpower may allow the wielder to employ the Item that caused this effect for a short interval before pain forces them to drop it, or the hand fails due to muscle or tendon damage. It is possible that the fire may not be extingished by conventional means. The fire will start at the point of contact and spread. Interestingly, nothing carried or worn is subjected to the fire. Optionally, any other living flesh touched will also alight.
4. Transformation - User is morphed slowly into a demonic entity, and if the item is held too long, the transformation will be complete and the user lost. Letting go of the item causes the effect to gradually reverse, but at 1/10th the rate of the inital transformation. Other possible forms may be substituted at the whim of the GM.
5. Freezing - User slowly freezes - starts as painful cold, progresses to frostbite and complete freezing. This will start at the point where the Item was touched, and then moves inwards as with the other effects, eventually killing the victim. The effect will continue indefinately, enshrouding the (dead) victim in ice.
6. Crumbling - User’s flesh turns to sand-like granules, falling away and leaving bare bones. Eventually unless magically countered, the victim will be completely skeletonized, and of course will die as major organs are consumed. This effect will only start after a delay upon handling the item, allowing for some use before the user begins their disintegration.
7. Phasing - User begins to fade away into nothingness, though a merciful GM might instead translocate the victim somewhere awful. As they fade, their weight and strength decrease (see Ring of Disappearance for details.)
8. Shrinking - User reduces in size gradually, eventually becoming smaller then the smallest insect. This is not fatal directly, but since the process continues indefinately, they will eventually reach a size where it is irrelevent if they are alive or dead, or they are eaten by a microbe.
9. Encorpulation - User begins to grow fatter and fatter, regardless of food consumption. This process continues until either stopped magically, or the victim dies of complications of their tremendous size.
10. Spiderspawn - Victim has bulbous growths similar to bubonic plague, but once they reach a couple of inches in size, they burst releasing a poisonous spider. This continues even after the victim's death. Each eruption causes a minor injury and may subject the victim to a poisonous bite if the spider is disturbed.
11. Bone Spurs - Victim begins growing sharp bony spurs in random locations, usually starting near the contact with the item was made. These will first appear as lumps and then eventually pierce the skin. If not reversed, Death will eventually follow from blood loss and infection. Those with the ability to regenerate may eventually resemble pincusions.
12. Possession - Victim has a beacon placed on them in the underworld. They will receive constant attempts at possession, and these attempts are at much higher rates of success then normal.
***From here on I added new ideas***
Everything the person touches turns to gold. At first a boon-copper and silver coins, buttons, sword hilts and the like turning to gold means more money, this rapidly becomes a bane, as food becomes inedible and drink becomes undrinkable. Unless countered with magic, the affected person will soon die of thirst, surrounded by gold.
14-Touch of Decay
The person's touch rots. Human skin decays in seconds, food goes bad, leather and metal rusts and corrodes over time. The affected person's weapons may end up as rusted pieces of metal and the person wil find it hard to feed themselves as the food he or she touches rots between being touched and reaching the mouth.
Starting at the point of contact with the item and moving in, the person ages, becomeing a doddering old person within days with all the problems of old age. Rather then killing them directly the effect then stops,leaving them without very long to live.
16-Aura of Evil
A bit of the evil aura on the item lingers. Civilians will be scared of the person, law enforcement will be more likely to stop and question him or her, and dark villians may think he or she is one of them.
The toucher becomes a magnet for trouble, from wolves and bears in wild areas to guards in dungeons to theives or unpleasent city guards in towns. And customs people will allways search the toucher at any international border.
First, the toucher's fingers and then the rest of their body becomes immaterial, which lasts until the toucher tries to pass through a wall-when the toucher becomes promptly solid with fatal and very messy results.
Starting at the point of touch and moving on, the toucher slowly changes into the villian from which the object was taken. The very last thing to change is the brain, which leaves the PCs with a horrible choice-kill their fellow PC quickly or end up fighting the villian all over again.
The toucher has nightmares that prevent them getting much sleep. Should he/she take sleeping pills or try using a sleep spell then he or she will end up in a fight in a dream, losing this fight will kill the toucher in the real world.
The toucher's hands go the colour of blood, meaning that gloves are needed to avoid misunderstandings.
22-Urge to Steal
The toucher has an urge to steal and it is a constant hassle to keep it under control, as the majority of times it would be a very bad thing to steal and maybe attract trouble from law enforcement/vigilantes.
23-I See Dead People
The toucher can see and hear ghosts, which whilst they can't hurt him or her, can and do constantly pester him or her for favours.
Spells that are meant to harm people that the toucher casts (fireballs, lightning bolts and the like) have a 50% chance of either hitting a fellow PC or an innocent NPC. Healing spells are unaffected.
Every full moon the toucher turns into either the classic wolf or some other creature (see the 30 Lycanthorpes submission for details.) The PC depending on the GM can be in control of his/her were form or just an animal.
The fingers of the toucher grow an inch per hour and become many jointed. Not a problem at first until they get ridiculously long.
The toucher is plauged by insect swams, rats, vultures, ect. Whilst not outright attacking the toucher or the PCs they are a pain in the neck and might spread disease.
An effect for one of the less serious games only. The toucher is bothered by loud theme music, which ruins ambushes, makes sleeping hard, and causes people to stare at him/her and the rest of the PCs. Bouncers will bar or at least try to bar the affected PC from clubs that play music.
29-Can I buy your soul please?
The PC is approched by a powerful demonic being trying to get him to sell his soul. If attacked, depending on the GM it will either fight back (and be a major menace, plus any PCs it kills ends up in Hell) or vanish in a puff of smelly brimstone. It can offer one big piece of help, but only in exchange for the PC's soul when the PC dies.
30-No fingers left
The PC's fingers drop off magically, leaving the PC with no fingers and unable to do anything that fingers are needed for, (holding weapons, scratching itches ect) but otherwise unharmed.
Additional Ideas (1)
The effect is not instantaneous, rather a gradual event that reaches it's summit at the end of the week. Voices begin to haunt the PC, they often hear questions about life and the general purpose of existance. The PC's teeth are gradually gaining sentience, and are going quite mad. With the inability to do anything but grind up food, every single tooth incessantly voices out it's despair. Magic can solve this, as can pulling out all of your teeth.
32-Not Of My Own
Involuntarily, the PC will speak the deepest darkest secret of another character in the room at random intervals. These are often horrible secrets that will distress the character. Though excellent for PCs who enjoy blackmail, other people may wish to silence him before he speaks out more.
This curse will not show until the PC is slashed or wounded. During battle or an accident when cut formed instead of a wound a mouth will appear. This mouth will belch out blood before it begins to mimic every action the original mouth does. Or it could also do as the curse in 32.
From then on, the PC will never have another dream or nightmare when he sleeps. Instead his subconcious forces visions from the dreams he would be having during his awakened state, the PC will have a difficult time discerning what is real, and what is fake.