“ A massive iron key - 2' length, 20 lbs forged with demonic faces from the bones and horns of demon-lords. When used with a massive portal - carefully built according to documents found in powerful books of evil knowledge, it will open into the realm of demons and allow them to flood into the world. The applications of this item for villains are obvious. Mortals touching this item are subject to [Effects_of_Touching_Powerful_Evil_Artifacts]”
“ The player characters, experienced and somewhat well known, hear rumors and travelers' tales about a distant area being overrun by dragons (or other terrifying monstrosities). The locals have sent them a message, begging for heroic aid.
When they investigate, they discover that nothing of the sort is going on. It turns out that a group of thieves wanted them out of the way so that they could rob them (or someone who would normally receive their protection).”
“ Thrown enchanted skulls make great necromantic 'grenades' releasing blasts of negative energy, incorporeal undead, swarms of flesh-eating worms, etc.”