Archbishop Midas of the Jovian Temple was a scourge to necromancers of all kinds, from the genuinely malicious to those who were merely talking to the dead with the consent of the families, sending many to burn at the stake, so after his death they took their revenge...and created the Bone Idol.
Thirty types of often magical ink that may be found in books or scrolls or occasionally just scrawled on a wall, with all kinds of uses.
The queen of a pocket kingdom, Zora is known for her command of dark magics, fashion sense that involves using armor grade metal in dresses and bustiers, and the stark contrast of her pale skin against her blood red lips and raven dark hair.
Often PCs get on the wrong side of powerful users of magic or break into enchanted tombs, either may get them on the wrong side of a curse.
Consider the idea of spontaneous genesis of life, as used to be belived. What strange kinds of life might arise from modern substances? What kind of vermin would a landfill produce, or an oil spill on the ocean?