“ Pick up a pathology/microbiology book, and add the diseases/syndroms to your game. Your players will freak out.
Coughed at? Diphteria. or tuberculosis?
Drunk from a muddy stream? Or just walked through? Well, let us introduce you to schistosomiasis...
Hit by a stream of energy? Too moch mana is ust like too much radioactivity - perhaps all mages could develop cancer early if too powerful...”
“ A plague is spreading trough the lands, the plague is actually an old woman carrying a stick. She walks from farm to farm spreading the plague. Can the PCs stop her without getting infected.”
“ As you emerge from the shop in the alleyway, not-too-distant clanging and stamping makes you wary. Further investigation reveals a massive Balgrian protest march flooding the main street, banners roaring about the inhuman conditions in which this ethnic group is forced to live. City guards stand helplessly by, beating up the odd protestor, but unable to hold back the flow. Onlookers throw vegetables at the Balgrians, and shout abuse.”