“ Pick up a pathology/microbiology book, and add the diseases/syndroms to your game. Your players will freak out.
Coughed at? Diphteria. or tuberculosis?
Drunk from a muddy stream? Or just walked through? Well, let us introduce you to schistosomiasis...
Hit by a stream of energy? Too moch mana is ust like too much radioactivity - perhaps all mages could develop cancer early if too powerful...”
“ The PCs encounter a strange set of artistic drawings done on the ground as they pass through a city. It has been done in chalks and no one saw who did it. Wizards might recognize the writing within the colored square as an obscure and dead language with a message stating that a prominent wizard and a retired bard have discovered how to populate Arcadia with the spirits of the dead!
Is it a local hoax, or are the PCs crossing the path of a very deranged and possibly dangerous mage?”
“ As far as everyone knows, the Maze has always been there; the strange pair of gates set in the side of a mountain a common feature in every painting of the area, no matter how ancient. One white, one red, nobody knows what they're made of but they resist any attempt to damage them; they're always slightly cool to the touch no matter the weather, they have a very reflective surface, and if you look at them in a bright light, sometimes it looks as if they glow on their own.
The important thing is what's on the other side of them, of course. The Maze itself is a strange place where the normal rules are suspended, and its own set takes their place. It's a place filled with puzzles and riddles, monsters and traps; it's always consistent with itself in any single run but is never the same two times around, and sometimes you could swear it has a sadistic streak, delighting in tricking the unwary adventurer.
It is a dangerous place, as so many people will rush to tell you; most people who go in never come out, and even those who do usually end up scarred for life. They also bring out with them enormous piles of riches, which is why people keep going in anyway.”