One of the strangest weapons deployed by Z'pl'rt the Mad
Admirals, I present to you the future of space warfare! No longer will you need to waste billions of credits on costly space battles, and millions of lives on planetary warfare with hostile cultures. For only a fraction of the cost of a heavy cruiser, I present you with a weapon capable of eliminating an entire solar system. "I present the Star Hammer!"
(A powerful and deviously simple weapon to make space warfare in any sci-fi game forever changed)
A plague has hit the local area.
In humans it affects only the most vulnerable, the children and the very old, and even than it's little more than a summer cold. 24 hours of sniffles and then it's gone, barely noticeable really.
To sheep however it is fatal and the whole economy of the area is in serious trouble. If this keeps up the area could well be facing famine.
Somebody (enter the PCs) must find the rare herbs needed to make a cure.