“ What if potions and tonics had negative side effects? Potions of increased strength cause violent tempers, or damage joints. What if potions of dexterity caused tremors, or palsy?
What if they were addictive, and had withdrawal symptoms?
Could someone make a bad batch? No one use the brown strength potion!”
“ The PC's end up in a strange world where the very rocks are made of gold and jewels.As such gold and jewels is worth very little, but the iron in their swords and belt buckles is suddenly worth a LOT.”