“ A Deity of some sort has unleashed a plague of bookworms or something like that in the area. Almost all spellbooks are destroyed, along with bardic and historical books.”
“ A healing potion which if drank by males (or women in male clothing) causes a short term (1 d6 hours) urge to dress in girl's clothing due to the high levels of estrogen in it.”
“ Could come across a band of refugees. Could have been thrown out of their town by a tyrant taking of their land, bought out by somebody unexpectedly, fleeing a battle they know is coming their way. Could be proof of what they are searching for, hints and tips of what is to come, or just to broaden the reality of the world.”