A young Noble and Holy Warrior
An ancient people built mystical fortresses made of melted stone; from the wall’s these fortresses defenders appeared to burn with a powerful energy and strike at their opponents with a supernatural force. Today most of these forts are abandoned and the art that made them lost.
Pick up a pathology/microbiology book, and add the diseases/syndroms to your game. Your players will freak out.
Coughed at? Diphteria. or tuberculosis?
Drunk from a muddy stream? Or just walked through? Well, let us introduce you to schistosomiasis...
Hit by a stream of energy? Too moch mana is ust like too much radioactivity - perhaps all mages could develop cancer early if too powerful...