“ In a crowded marketplace, a man is standing on a soapbox, orating. Some of the crowd are cheering, some hissing, some standing around saying 'I can't hear a bl**dy word he's saying'. It's a hustings for an election. The PCs can either leave, or stay and listen. If they do the latter, then they can vote too, and they might get quite involved in the cheering. Depending on who wins they might get quite involved in the post-election brawl too...
There are numerous possibilities with this encounter: the PCs might end up talking to one of the nervous candidates before their speech, and offer encouragement and support. Of course this candidate may well turn out to be someone with outspokenly unorthodox views, and the crowd don't take kindly to s/his supporters. Or maybe the seemingly innocuous candidate turns out to be a complete racist, and the PCs wander off embarrassedly, pretending they weren't talking to this person five minutes ago.”
“ Pick up a pathology/microbiology book, and add the diseases/syndroms to your game. Your players will freak out.
Coughed at? Diphteria. or tuberculosis?
Drunk from a muddy stream? Or just walked through? Well, let us introduce you to schistosomiasis...
Hit by a stream of energy? Too moch mana is ust like too much radioactivity - perhaps all mages could develop cancer early if too powerful...”
“ When night falls, we find peace in the knowledge that daytime will return soon, and vice versa. But what if the world was split: daytime and night are two different, coexistent worlds, each with it's own laws and rules. At dawn and sunset, our soul switches to inhabit our other being, our 'twin'.”