“ Draw the party together as debtors to the local lord, king, head of the thieves guild, or mercenary clan, who is forcing them to work together to pay off their debts.”
“ Feral teenagers:
Teenagers who run away from home to live in the wilderness may become feral. As they become more and more feral, they gain some supernatural powers (a la Peter Pan - ability to fly, things they imagine come true - possibly quite powerful), but at the expense of their humanity and ability to speak, comprehend complex subjects, etc. Maybe they have a leader: the most feral of them all.
A regression into a fantasy childlike state.”
“ A group of humans living in a mountainous area have spent generations mining, drinking home made liquor, and generally not spreading the gene pool around enough. The end result is a sub-race of humans who no longer have necks, rather their heads protrude from the upper portion of the torso between the shoulders. They have beards, and lacking the ability to turn their heads, can only see what they are directly facing. They are simple and to the point, and direct to the point of bluntness.”