To all space explorers, rogue traders and Federation colonisation and expeditionary force officers!
Thirty new alien species have been discovered. You are well-advised to inform yourselves, as to engage these entities correctly, without risk of harm to yourself or to the interests of Terra.
Ten of the described species are human in origin, yet modified to such a degree that they no longer need to be considered human.
Another ten are civilisation-building aliens competing with Terra for available space.
The final ten entries are remarkable life forms that display sapience, without using it to create civilisations. Caution is advised.
Pick up a pathology/microbiology book, and add the diseases/syndroms to your game. Your players will freak out.
Coughed at? Diphteria. or tuberculosis?
Drunk from a muddy stream? Or just walked through? Well, let us introduce you to schistosomiasis...
Hit by a stream of energy? Too moch mana is ust like too much radioactivity - perhaps all mages could develop cancer early if too powerful...