The players see a small shrine to the local nature deity just of the trail. Before they even approach it, they can smell the foul stench of rotting meat. If they inspect the shrine, they can see it has been desecrated by rotting organs in the last few days. There is no mistaking it for an obscure ritual, the organs are thrown everywhere, not left in specific places as in sacrifice.
If the players try to clean the shrine, they will soon find it has been boobytrapped to fling sharp splinters covered in the rotting gore in every direction. While only doing a few points of damage, they injured players will likely take sick soon unless they get medical attention.
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They say you give up a few things, chasing a dream. In those mists that's the literal truth, for every dream of yours that comes true, a piece of yourself, mind, body, or soul, gets taken by the mist. Worst part is, you won't even know what the cost of your dreams are until you go to leave, and by then you might not even have a mind left to change...
A fragment of the mists of creation, drawn to those desperate to make their dreams come true. Suitable for any magical fantasy setting.