“ A massive iron key - 2' length, 20 lbs forged with demonic faces from the bones and horns of demon-lords. When used with a massive portal - carefully built according to documents found in powerful books of evil knowledge, it will open into the realm of demons and allow them to flood into the world. The applications of this item for villains are obvious. Mortals touching this item are subject to [Effects_of_Touching_Powerful_Evil_Artifacts]”
“ Pick up a pathology/microbiology book, and add the diseases/syndroms to your game. Your players will freak out.
Coughed at? Diphteria. or tuberculosis?
Drunk from a muddy stream? Or just walked through? Well, let us introduce you to schistosomiasis...
Hit by a stream of energy? Too moch mana is ust like too much radioactivity - perhaps all mages could develop cancer early if too powerful...”
“ In this dungeon, the monsters will not be hostile unless you take something without permission. If you do take something, the monsters inside will consider it stealing and attack you.”