“ <br />
Real world scientists have accidentally opened a tear in the fabric of reality, transporting their laboratory into the game world. Unable to repair and/or refuel their equipment in this (to their minds) primitive world they are now trapped.”
“ War of the Roses as a campaign plot. Two noble lines converge somehow, each line thinks it has the rightful claim to the throne. Deciding this long ago was handled by some divine intervention, requiring both houses to come together at some point. They aren't so willing to get together this time. Civil war, or a new king?”
“ What if cancer is not an ailment if one has a will powerful enough, and knows what do do. What if one using the right techniques could control it and use it to become immortal, or to grow into something else?”