“ In a small, genetically isolated region it is not uncommon for the locals to have three arms. The third arm is generally a second right arm that is a good bit weaker than a normal arm and is generally held against the chest. This hird arm is most often used to carry small things, though some of the more skilled craftsmen have learned little tricks with their third arm.”
“ Pick up a pathology/microbiology book, and add the diseases/syndroms to your game. Your players will freak out.
Coughed at? Diphteria. or tuberculosis?
Drunk from a muddy stream? Or just walked through? Well, let us introduce you to schistosomiasis...
Hit by a stream of energy? Too moch mana is ust like too much radioactivity - perhaps all mages could develop cancer early if too powerful...”
“ As they travel they notice a horrible rotten smell. As they travel it gets stronger and stronger forcing them to cover their noses and mouth less they choke on the horrible smell. Stream full of dead fish. Spawning trout die in mass quantities after they spawn littering areas with dead fish dying and deteriorating in the sun.”