“ The members of the party has unknowingly been infected by a mysterious plague and have been spreading the virus for quite some time now while adventuring. They start to hear rumors of all the cities in quarantine after they travelled trough. Will they discover the source of this? Will people start to avoid them, try to kill them?”
“ The religion believes in reincarnation, but that you will be reborn in the past. People of today are those re-born of tomorrow, with some discarded as trash. The most pure will be eventually reborn in the mythical paradise-like past, where people lived for hundreds, or maybe even thousands of years.
This goes nicely with beliefs into foresight (you know a little about the future because you have been there), but also to many complaints of how things are going always from bad to worse.”