“ A village where everyone goes blind sometime during puberty. What could be causing this? Perhaps something in their diet. Or some malignant gene. How would an entire village where only young childen can see function?”
“ The Mad Pope is a wandering mercenary. He is very well deranged as he considers himself to be the pontiff of the dominant faith. His robes are tattered, his mitre has seen better days and there are surely lice in his long ratty beard. What sets him apart from most addle-pated would be holy men is that he has armor under his robes and carries a large crossbow and several one-handed swords. While many would discout him as just another lunatic, for some reason, he inspires others around him and has demonstrated the ability to lay on hands and heal the wounded.”
“ Pick up a pathology/microbiology book, and add the diseases/syndroms to your game. Your players will freak out.
Coughed at? Diphteria. or tuberculosis?
Drunk from a muddy stream? Or just walked through? Well, let us introduce you to schistosomiasis...
Hit by a stream of energy? Too moch mana is ust like too much radioactivity - perhaps all mages could develop cancer early if too powerful...”