“ When was the last time a character caught a cold or flu? Real people get them every now and again even with solid heating and dry interiors. Your characters are out in the cold and wet, and even inside is not always dry and warm. Imagine having to stop your dungeon crawl, sitting in a tight defensive position, while you all are feverish.”
“ What if cancer is not an ailment if one has a will powerful enough, and knows what do do. What if one using the right techniques could control it and use it to become immortal, or to grow into something else?”
“ A caravan is traveling through the desert. The party is hired to capture a man who is in the caravan, and it must be done quietly, so that nobody else knows. They are given the man's name, and the fact that he is a mage, but no other information about him. The catch is that the caravan consists of ten wagons, with at least thirty or forty guards.”