“ In the middle of a desert in an oasis is a single prospering oak tree. Near the tree is a large pool of water. Drinking from the water is said to give you eternal life but really only extends your life for as long as you continue drinking from it. Those that have found it and left, have never found it again. Some search for it still.”
“ On a location with numerous webs, and at least one big spider, there is a something inside a cocoon. It is humanoid in shape, still moving. If the heroes free it (not before they kill or drive away the spiders), they meet a ... zombie!
The poor zombie wandered the dungeon alone, and tried to kill a big living creature (= a spider). The spider used the usual treatment, even if this victim did not look tasty. The zombie can be easily killed as any other zombie. It got but several doses of spider-poison, so can be something worth if it is extracted. You can mention to a druid or ranger the fact the spider had no poison anymore.”
“ A secret MLM (pyramid) company that offers eternal life, but in fact it transfers the life forces of its members to those position 'above'. If you get high enough, (meaning you get enough new members) you start to enjoy the benefits. Maybe a willing sacrifice is much more effective for the transfer. But no one says, that a suddenly unwilling member, threatening to tell the authorities, may not loose it involuntarily... thus start people to vanish, and aged corpses are deposited somewhere safe.”