“ The PCs have been traveling for a long time down the same stretch or round with no sign of anything suspicious. As they cross over to the next hill they see a gigantic splater of blood with a bleached dragons scull in the center of it. It the dragon skull's mouth is a tattered backpack with something wiggling inside of it.”
“ What if cancer is not an ailment if one has a will powerful enough, and knows what do do. What if one using the right techniques could control it and use it to become immortal, or to grow into something else?”
“ You receive a vision of a rooftop 'somewhere close by', where a rare moss grows; in the vision, you know the moss is suitable for greatly enhancing the effects of certain types of potions. Now go and find that rooftop. Don't fall off. (Of course, rooftop runners *will* be taken for miscreants by the local City Watch....)”