“ Pick up a pathology/microbiology book, and add the diseases/syndroms to your game. Your players will freak out.
Coughed at? Diphteria. or tuberculosis?
Drunk from a muddy stream? Or just walked through? Well, let us introduce you to schistosomiasis...
Hit by a stream of energy? Too moch mana is ust like too much radioactivity - perhaps all mages could develop cancer early if too powerful...”
“ While traveling trough farm land the PCs come upon a merchant sitting on a wrecked wagon without a mule attached to it, hid face burrowed in his hands. He explains that he was robbed by petty goblins, unable to defend himself he had retreated. He asks the PCs to help him retrieve the mule before the goblins roast it, as a reward they may keep his goods. How hard can it be?”
“ Imagine that all the humanoid and demi-human laguages are actually the same, but pronounced with outrageous accents and bizarre idiom. All the elves have a French accent, all the Dwarves have Swedish, Dragons have a Pakistani accent...”