“ Real World: some Indians in the Amazon treat their eyes with a traditional potion applied with palm leaves. Brutally painful, the drug alters vision, giving the jungle's dense green walls greater texture and dimension. You could adapt this to desert or swamps, or other hard to navigate regions.”
“ The PCs are accosted in a major city containing at least one famous fortuneteller / prophet of the future. They are informed that their as-yet-unborn child will (insert terrible evil), and that, although they are very sorry, the PC must be executed to keep this from happening.”
“ War of the Roses as a campaign plot. Two noble lines converge somehow, each line thinks it has the rightful claim to the throne. Deciding this long ago was handled by some divine intervention, requiring both houses to come together at some point. They aren't so willing to get together this time. Civil war, or a new king?”