No one is really sure what a Xamek is, or if they even exist
Appearing as mutilated humanoids with large heads, Nihilids are terrifying to encounter. They are thankfully rare.
Dimensional Science has started to unlock the understanding of the fact that the universe is made of layers, and these layers while interacting with each other, are very distinct from each other.
What is arcanotech? It's breaking the laws of physics for fun and profit.
A hostile race discovered through dimensional boring. The first encounter with the violent and nomadic Tarxan occurred in Neo-Constantinople of the Eurasian Alliance, hence the Turkish/Central Asian rooted name.
"Living in a town that sits on a dimensional nexus can wear thin after a while. It's not so much the crawling shadows, bizarre weather, or late night visitors from places that never existed; but carrying on with your normal life and trying to act like nothing out of the ordinary is going on in your little corner of the world that gets to you."
A small rural town with surreal secrets, that happens to be situated on a dimensional crossroads, suitable for modern day supernatural/mystical/horror campaigns.
If you want to add a "supernatural" touch to your campaign, define the rules of magic and the universe. Make your players comfortable with those rules. Then your new supernatural creatures must then break those rules.