“ What if cancer is not an ailment if one has a will powerful enough, and knows what do do. What if one using the right techniques could control it and use it to become immortal, or to grow into something else?”
“ A powerful wizard that the PCs encounter is completely silent. He does not speak and cannot be heard as he moves. Even his spells are silent, but his magic is just as potent.
He has a tendency to summon invisible chairs, place foes in invisible boxes of force, and other 'mime tricks'.”
“ How about a dragon how cheerfully rules over a kingdom; his people all know him for what he is, and dragons are looked upon as wise and benevolent creatures. Dragonslayers from other kingdoms coming to free it from 'tyranny' are likely to get beaten to death by peasants with cast iron skillets.”