“ What if potions and tonics had negative side effects? Potions of increased strength cause violent tempers, or damage joints. What if potions of dexterity caused tremors, or palsy?
What if they were addictive, and had withdrawal symptoms?
Could someone make a bad batch? No one use the brown strength potion!”
“ One morning, the sun does not rise. It seems that a great darkness has settled across the kingdom - at first, it is merely an inconvenience, but as time passes and plants begin to sicken and die, some action must be taken. As the deluded King plans the sacrifice of fifty tender virgins in the name of the Sun God, rumours spread of an ancient barrow uncovered in the hills...”
“ The PCs discover a large white ball in the branches of a tree, or in a niche in a cave. Unless magically examined, or by a PC with a specialty in insects, it is a plain, smooth white ball. After a short time, it hatches and releases hundreds of spiders, cockroaches, some other nasty bug”