“ Magical curses are rarely cast, as if cast on someone for fun or purely maliciously and the person cursed has not done something seriously wrong, it tends to ricochet back on the curser. Therefore the few who do get cursed are shunned by most people as genuinely guilty,and few will help them.”
“ The players encounter an organization dedicated to toppling tyrannous governments; both good and evil. Secretly, they are led by the twin daughters of Lucifer / The Lightbringer / (Generic Adversary God). These daughters have an appropriate set of divine or demonic powers, but strictly speaking, are not evil.”
“ If you want to add a 'supernatural' touch to your campaign, define the rules of magic and the universe. Make your players comfortable with those rules. Then your new supernatural creatures must then break those rules.”