“ A village where everyone goes blind sometime during puberty. What could be causing this? Perhaps something in their diet. Or some malignant gene. How would an entire village where only young childen can see function?”
“ The PCs are sent with a diplomat to another country to protect him and do his bidding. There may be some espionage, rescuing, downright bullying, etc. Could make a nice medieval, special operations background.”
“ A new substance is found in an out of the way area and kept very quiet. It is found to make a perfect counterfeit diamond. Only the most expert of expert appraisers would even have a hope of noticing that it is fake. Only one problem: if it gets wet it starts to slime and if it is saturated, it turns into a glob of gel.”