“ You pass through a woodland with a floor that seems remarkably clean of debris. Suddenly your attention is drawn to a twisted bit of wood by the trail side, a short broken twig with several stubs of branches along its length and most of the bark missing. When you reach it, the twig blurs and turns into a small brown lizard, caught in the middle of its body-twisting run. The little reptile darts away down the trail with impossible speed, no doubt magically enhanced, and is lost to sight in a moment. Now someone knows you are coming...”
“ The secret for immortality has been discovered by an eccentric wizard/mad scientist. Its found you need to reapply once a month. As people stop dying, and the birth rate increases exponentially, people are forced into homelessness, because of the need for food reamins the same, and food is not being produced fast enough to feed the undying population. The PCs have to find the creator and kill him, and destroy production, to save the world from undying, unending torture from hungryness.”
“ A PC Conjurer or summoner, basically any mage whose sole purpose in life is summoning creatures to aid in battles and various situations, is cursed with a hex, and needs to find a way to undo the curse...before he goes mad, or his fellow PCs throw him out of the party, or worse.
Everything he/she summons, never goes away. So you'll have to figure out what the heck to do with that dire bear or fire elemental once it's done fighting the orcs for you. Eventually a caravan of bizarre creatures either annoyingly ends up following the summoner around, or they go off to cause mayhem elsewhere. Bad news for the poor spell-caster regardless.”