“ What if the sources of precious metal in the realm all failed, so that the only sources for gold and other precious metal were hostile foreign lands? Gold coinage might become increasingly rare, resulting in hoarding. Player characters that appear with masses of treasure might be suspected of being in the pay of foreign powers.”
“ A village where everyone goes blind sometime during puberty. What could be causing this? Perhaps something in their diet. Or some malignant gene. How would an entire village where only young childen can see function?”
“ The heroes stop in a small town ready to restock their traveling supplies and feed for their animals. All of the villagers are starving, and there is no food to be had. If the PCs are quick witted, their noble steeds might be slaughtered for food.”