“ What if you send the players in a dungeon that was already raided? Maybe you could have traps that are already set off, or the corpses of monsters etc.”
“ A weapon of war created by an extinct race, this rat appears normal but is a simulacrum - beneath it's mangy fur is a body of bronze. Commanded by words in a lost language, wherever it goes a virulent and lethal plague follows. The cure is similarly obscure.”
“ Another real world thing. White tea. Can only be picked two days a year, the two days before the flowers blossom. Could be a similiar plant that...is the deadliest poison known, cure known diseases or psychosis, or a potent herb that just tastes awesome.”