“ Pick up a pathology/microbiology book, and add the diseases/syndroms to your game. Your players will freak out.
Coughed at? Diphteria. or tuberculosis?
Drunk from a muddy stream? Or just walked through? Well, let us introduce you to schistosomiasis...
Hit by a stream of energy? Too moch mana is ust like too much radioactivity - perhaps all mages could develop cancer early if too powerful...”
“ The mage who invented teleportation knew nothing about the ten-dimensional cosmos, so was perplexed that the subjects sent through the portal arrived horribly scrambled, having been randomly rotated through several of the hidden six dimensions.”
“ The party is walking through the forest at night when they come upon a clearing. Half a dozen black-robed corpses lie scattered across the ground, and a pentagram of blood is shoddily drawn in the dirt.
It seems these people summoned something they could not control. Whether or not the demon returns is up to the GM, but it would be just as rich if the demon never returned, and for the rest of the night, every stray sound or odd shadow will be jumped at!”