“ Foot Coral. It attatches to a foot like moss, almost gluing itself to an organism. It gets its food supply from the ground, and does not leech off the host in any way. It is not a malignant organism, and is entirely harmless. But it only grows on human feet, and even then, never on the left foot. An organism that it grows on can feel touch through the coral, but not pain. Removal of the coral is painless, but why would you want to?
Texturally, if fells like a dry, non slimy amoeba.”
“ With a huge number of sacrificial victims, another realm long ago secretly bound a Prince of the land spirits, Iorstonn by name, thus ensuring the fertility, and improving the magical defences, of their realm. But binding that Prince to one spot has disrupted the weather and magical patterns (ley lines?) over half the continent. Things have become bad enough that a coalition has been formed to rectify the situation, once divinations have established the cause.
Your party is one of the teams assembled to do the rectification: find the binding object and steal it ('so that we can destroy it here in our realm, of course'...*) or destroy it over there. Presumably the Prince will be grateful to his rescuers and angry at the binders, but with a greater spirit like Iorstonn one can never be sure: such beings are 'tricksy'.
* Of course, the rulers of our realm might want to control Iorstonn for their own ends...”
“ Temple of some malign being invites you warmly and offers help (curing,needed spell etc) for some minor sacrifice . Sacrifices must be everytime bigger to work - up to living inteligent creatures. Maybe you pay some other price,too...”