“ A secret MLM (pyramid) company that offers eternal life, but in fact it transfers the life forces of its members to those position 'above'. If you get high enough, (meaning you get enough new members) you start to enjoy the benefits. Maybe a willing sacrifice is much more effective for the transfer. But no one says, that a suddenly unwilling member, threatening to tell the authorities, may not loose it involuntarily... thus start people to vanish, and aged corpses are deposited somewhere safe.”
“ The PCs are sent with a diplomat to another country to protect him and do his bidding. There may be some espionage, rescuing, downright bullying, etc. Could make a nice medieval, special operations background.”
“ Adventurers are to capture an unknown monster for examination (for a sage or wizard) but they are themselves captured by the monsters, and researched.”