“ Animals have parasites and diseases, so do plants, there are even bacteria that cann dissolve oil spills or plastic or what have you - why couldn't there be a disease living off magic - a magic item could be infected, losing power and speading the plague to other equipment it contacts, while a magic user would slowly lose his powers and contaminate all he works with or casts a spell at...”
                        
                     
                                    
                        “ Idea from the Aeneid. Could make an intriguing encounter when searching for firewood...'Quite near there happened to be a mound of earth, at the highest part of which were growing thickets of cornel and a dense cluster of spiky myrtle-stems. I went up there and tried to wrench the green growth from the ground to provide a leafy covering for our altar. There I was confronted by a horrible and astounding miracle. For from the first bush which I tried to break off...blood oozed in dark drops, fouling the earth with its spots...A piteous moan came from the base of the mound and I heard a human voice answering me: 'Why, Aeneas, must you rend a poor sufferer? I am buried here...for I am Polydorus. Here death overpowered me in a crop of piercing iron-pointed spears. And so a crop resembling javelins has grown over me...''”
                        
                     
                                    
                        “ Pick up a pathology/microbiology book, and add the diseases/syndroms to your game. Your players will freak out.
Coughed at? Diphteria. or tuberculosis?
Drunk from a muddy stream? Or just walked through? Well, let us introduce you to schistosomiasis...
Hit by a stream of energy? Too moch mana is ust like too much radioactivity - perhaps all mages could develop cancer early if too powerful...”