“ War of the Roses as a campaign plot. Two noble lines converge somehow, each line thinks it has the rightful claim to the throne. Deciding this long ago was handled by some divine intervention, requiring both houses to come together at some point. They aren't so willing to get together this time. Civil war, or a new king?”
“ A terrible teleportation incident makes inter-demihuman chimaera of all the PCs. Quoth Master Adams: 'I teleported home one night / with Ron and Sid and Meg / Ron stole Meg's heart away / and I got Sidney's leg.'”
“ Diseased people, (leprosy or any other such fear inducing disease) when traveling, will often times wear a cloak that entirely covers their body and ring a bell as they travel, used as a warning for any others to stay away. Could be used for a disguise or safe passage. ... you meet strangely cloaked people, sometimes ringing a bell. 'Please give us something to eat, mighty heroes!' This is time to show how good they are.”