“ A certain type of demon cannot not be hit by ranged weapons or attacks. Attacks have to be made up close and personal for the damage to mean something. Ranged attacks are to impersonal.
Possibally a way to make the ranged attacks more meaningful would be to coat the arrow head or what not with the shooters blood. Of course, they'd better be a good shot, otherwise they're wasting arrows and already bleeding to boot.
Spells: wizards might have half or no effect, preist might work due to divine intention.”
“ Actually a real-world fungus, just heard about it. A fungus that tastes well and all, no ill effects. UNLESS you consume some beverage, even 3 (three) days after eating it. Then you become really sick, pains, vomiting, all the fancy stuff. Was really used to cure alcoholism. May be a joke or to make sure the heroes spend their time focused on the mission.”