“ Pick up a pathology/microbiology book, and add the diseases/syndroms to your game. Your players will freak out.
Coughed at? Diphteria. or tuberculosis?
Drunk from a muddy stream? Or just walked through? Well, let us introduce you to schistosomiasis...
Hit by a stream of energy? Too moch mana is ust like too much radioactivity - perhaps all mages could develop cancer early if too powerful...”
“ You receive a vision of a rooftop 'somewhere close by', where a rare moss grows; in the vision, you know the moss is suitable for greatly enhancing the effects of certain types of potions. Now go and find that rooftop. Don't fall off. (Of course, rooftop runners *will* be taken for miscreants by the local City Watch....)”