“ Magical curses are rarely cast, as if cast on someone for fun or purely maliciously and the person cursed has not done something seriously wrong, it tends to ricochet back on the curser. Therefore the few who do get cursed are shunned by most people as genuinely guilty,and few will help them.”
“ Poison can only ever be the tool of a murderer - as such, alchemists are tightly regulated by the Crown, and anyone found in posession of an unknown substance is forced to taste it themselves.”
“ A village where everyone goes blind sometime during puberty. What could be causing this? Perhaps something in their diet. Or some malignant gene. How would an entire village where only young childen can see function?”