“ Feral teenagers:
Teenagers who run away from home to live in the wilderness may become feral. As they become more and more feral, they gain some supernatural powers (a la Peter Pan - ability to fly, things they imagine come true - possibly quite powerful), but at the expense of their humanity and ability to speak, comprehend complex subjects, etc. Maybe they have a leader: the most feral of them all.
A regression into a fantasy childlike state.”
“ The members of the party has unknowingly been infected by a mysterious plague and have been spreading the virus for quite some time now while adventuring. They start to hear rumors of all the cities in quarantine after they travelled trough. Will they discover the source of this? Will people start to avoid them, try to kill them?”
“ In the harbour of a major city a large and terrifying ship made of human nails docks. Nobody seems to inhabit this ominous vessel, someone needs to go on board and unveil the mystery. In comes the PCs.”