“ Mining in a certain area turns all exposed skin (maybe just parts that are actively disturbing the chemicals that cause the reaction) of the those doing the mining to a dark blue color. Will wear off taking as many years/days spent in the mine. ... meeting a party of blue-skinned humans armed with pick-axes etc. Strange disease? Demon offspring? Curse? If they meet only one ex-worker, they will very carefully listen to any stories he says, no matter if drunken or insane, or just makes up to get a beer.”
“ Made from the tears of a bound goddess, this magical wine has the power to charm or dominate any who imbibe even the faintest quantity. Once affected, it remains dormant until the victim hears a special magical phrase, upon which they will be magically bound to the speaker. Enterprising villains could drop this into the water supply of an important city..”
“ A great treasure has been stolen from the Palace and taken to the nearby Temple to the Bitch-Goddess Atrath Klee. The King demands that the party go and retrieve it - the only snag is that the Temple is guarded by potent magic that will kill any male who steps inside. It's just as well that the King has a stash of Girdles of Gender Alteration for just this circumstance.”