“ The lengthy process to do something necessary or a magical scroll needed is inscribed on the other side of a great tapestry and can't be removed. For more fun it could be in the kings throne room. Try to hide in shadows with a 20*5 (yards/meters) monstrosity!”
“ The PCs are accosted in a major city containing at least one famous fortuneteller / prophet of the future. They are informed that their as-yet-unborn child will (insert terrible evil), and that, although they are very sorry, the PC must be executed to keep this from happening.”
“ The members of the party has unknowingly been infected by a mysterious plague and have been spreading the virus for quite some time now while adventuring. They start to hear rumors of all the cities in quarantine after they travelled trough. Will they discover the source of this? Will people start to avoid them, try to kill them?”