“ A friendly human hunter has a talk with you about what you are doing here, and how is the weather. He advises you to not disturb the animals, tend to any fire you set, etc. This is actually a werewolf checking his territory, and if you are not to his liking, he may ambush you with his pack later.”
“ The heroes stop in a small town ready to restock their traveling supplies and feed for their animals. All of the villagers are starving, and there is no food to be had. If the PCs are quick witted, their noble steeds might be slaughtered for food.”
“ A city is being plagued by a swarm of winged mice. The vermin can get anywhere, and they can easily avoid their normal predators by simply flying away from them.”