“ The secret for immortality has been discovered by an eccentric wizard/mad scientist. Its found you need to reapply once a month. As people stop dying, and the birth rate increases exponentially, people are forced into homelessness, because of the need for food reamins the same, and food is not being produced fast enough to feed the undying population. The PCs have to find the creator and kill him, and destroy production, to save the world from undying, unending torture from hungryness.”
“ A Deity of some sort has unleashed a plague of bookworms or something like that in the area. Almost all spellbooks are destroyed, along with bardic and historical books.”
“ Made from the tears of a bound goddess, this magical wine has the power to charm or dominate any who imbibe even the faintest quantity. Once affected, it remains dormant until the victim hears a special magical phrase, upon which they will be magically bound to the speaker. Enterprising villains could drop this into the water supply of an important city..”