“ The PCs are sent with a diplomat to another country to protect him and do his bidding. There may be some espionage, rescuing, downright bullying, etc. Could make a nice medieval, special operations background.”
“ Nearly every primitive culture has had rituals and celebrations to guarantee the proper passage of the seasons and to ensure the fertility of crops and animals. Oversight of these ceremonies was generally the provenance of local kings or priests.
Suppose that the adventurers dispatch one of these fellows. The local peasants may become hysterical, fearing famine and death will stalk the land. Alternatively, they may want one of the new heroes to become king. For a while, this can be a good thing, but the first time that the crops fail, the superstitious locals will want to sacrifice their new leader.”
“ Actually a real-world fungus, just heard about it. A fungus that tastes well and all, no ill effects. UNLESS you consume some beverage, even 3 (three) days after eating it. Then you become really sick, pains, vomiting, all the fancy stuff. Was really used to cure alcoholism. May be a joke or to make sure the heroes spend their time focused on the mission.”