“ A casual remark by one of the party about something met on a previous adventure leads to a summons to and grilling by the Mages' Guild (or equivalent), probably resulting in an expedition back to that area to recover the things for study by the Guild. The party's presence will be 'requested' for this expedition.”
“ A character who is undergoing changes of personality (like buying off mental disadvantages - flaws - or changing alignment) might confront personifications of aspects of his personality in dreams: a griffon representing the courage he needs to face a terrible foe, or a satyr standing for the lecherousness a warrior must overcome to be admitted to an order of knights who must uphold vows of chastity.”
“ What if cancer is not an ailment if one has a will powerful enough, and knows what do do. What if one using the right techniques could control it and use it to become immortal, or to grow into something else?”