“ Mining in a certain area turns all exposed skin (maybe just parts that are actively disturbing the chemicals that cause the reaction) of the those doing the mining to a dark blue color. Will wear off taking as many years/days spent in the mine. ... meeting a party of blue-skinned humans armed with pick-axes etc. Strange disease? Demon offspring? Curse? If they meet only one ex-worker, they will very carefully listen to any stories he says, no matter if drunken or insane, or just makes up to get a beer.”
“ During a storm the PCs come upon a little boy that plays in the rain. Upon further inspection they discover that he has one eye and a long tongue lolling in its mouth. Spit dripping. It is a demon from beyond that can access our realm during storms, it eats all heads that are not its own, living and dead.”
“ A slow, stupid creature that crawls onto people and latches onto them, often on feet, hands, and other extremities, numbing down the area and slowly feeding on it. It's easy to avoid while awake, but nearly impossible to remove once attached. Many an adventurer has been forced to hack off an arm or leg after waking with a Stoneleech wrapped around it. Sleep with one eye open! (This idea came from 'Wizard's Rule')”