“ Pick up a pathology/microbiology book, and add the diseases/syndroms to your game. Your players will freak out.
Coughed at? Diphteria. or tuberculosis?
Drunk from a muddy stream? Or just walked through? Well, let us introduce you to schistosomiasis...
Hit by a stream of energy? Too moch mana is ust like too much radioactivity - perhaps all mages could develop cancer early if too powerful...”
“ You wake in a pub and see that it's full of were creatures, and they're all staring at you with a scared look on their faces. As you continue on into the pub you look at your arm. You notice that your arm is covered in thick brown hair. As you continue on into the pub you look in a mirror, and staring back at you is a 7 foot werebear. As you continue into the pub people start to shy away form you. Once you go the bar you ask the weretigress that's the bartender and begin to ask her why everyone is shying away from you, and she begins ro tell you why.”
“ A village where everyone goes blind sometime during puberty. What could be causing this? Perhaps something in their diet. Or some malignant gene. How would an entire village where only young childen can see function?”