“ Pick up a pathology/microbiology book, and add the diseases/syndroms to your game. Your players will freak out.
Coughed at? Diphteria. or tuberculosis?
Drunk from a muddy stream? Or just walked through? Well, let us introduce you to schistosomiasis...
Hit by a stream of energy? Too moch mana is ust like too much radioactivity - perhaps all mages could develop cancer early if too powerful...”
“ Could come across a band of refugees. Could have been thrown out of their town by a tyrant taking of their land, bought out by somebody unexpectedly, fleeing a battle they know is coming their way. Could be proof of what they are searching for, hints and tips of what is to come, or just to broaden the reality of the world.”
“ After a long night of reveling and merriment celebrating their latest victory, one of the PCs awakens with his/her head shaved and a large ornate tattoo on top of their head. Tacky, yes but also a painstaking work of art that has left them with a headache to beat their hangover. The kicker? It is a huge symbol of the god of Evil, Assassins, the Drow, Munchkins, something really really offensive”
