“ Pick up a pathology/microbiology book, and add the diseases/syndroms to your game. Your players will freak out.
Coughed at? Diphteria. or tuberculosis?
Drunk from a muddy stream? Or just walked through? Well, let us introduce you to schistosomiasis...
Hit by a stream of energy? Too moch mana is ust like too much radioactivity - perhaps all mages could develop cancer early if too powerful...”
“ Diseased people, (leprosy or any other such fear inducing disease) when traveling, will often times wear a cloak that entirely covers their body and ring a bell as they travel, used as a warning for any others to stay away. Could be used for a disguise or safe passage.”
“ A large river that is continuously covered in a thick layer of fog. There will be either a rope ferry to get across or possibly a boat that is rowed across by worshippers of the water elementals. It is very thick fog to the point where it even muffles voices even at close range and visibility even beyond a foot is almost impossible.”